Pascale Romby

Marianne Grunberg-Manago award winner 2025

Profile

Pascale Romby is Emeritus Research Director at the CNRS since July 2025. She led the team “Messenger RNA and Regulatory RNA in Bacteria” team from 2004 to 2025 within the “RNA Architecture and Reactivity” research unit (UPR9002 CNRS) at the Institute of Molecular and Cellular Biology (IBMC).

A biochemist and molecular biologist by training, Pascale Romby completed her studies in Paris and at the University of Strasbourg (formerly Louis Pasteur University). She joined the laboratory of Professor Jean-Pierre Ebel, where she defended her doctoral thesis in 1983 and then her “Doctorat d’Etat” in 1986 under the supervision of Dr. Richard Giegé (IBMC, Strasbourg). Through her collaborations, she uncovered the roles played by the sequence, the RNA modifications, and the tRNA structure not only in the decoding of genetic information and protein biosynthesis but also in their non-canonical functions. The study of the links between RNA structure and function has been a driving force throughout her career.

In 1987, she was recruited at the CNRS as a researcher in the team led by Dr. Chantal Ehresmann and Prof. Bernard Ehresmann, whose main focus was the study of the bacterial ribosome. After contributing to projects on translation initiation and the study of ribosomal components, such as 5S rRNA, she shifted her focus to the role of mRNA structure in the regulation of translation in Escherichia coli, notably in collaboration with Dr. Mariane Grunberg-Manago and Dr. Mathias Springer (IBPC). In 2005, encouraged by Professor Eric Westhof (director of the CNRS research unit “Architecture and Reactivity of RNA” 2005-2016), she established her own team dedicated to the study of “regulatory RNAs and bacterial mRNAs” across diverse bacteria species. Her work aimed to compare regulatory mechanisms at the translational and post-transcriptional levels, as well as adaptation strategies among phylogenetically distant species. In collaboration with Professor François Vandenesch (CIRI, Lyon), her team pioneered the mapping of regulatory networks involving numerous RNAs in the pathogenic bacterium Staphylococcus aureus. These networks link central metabolism, cell density, carbon source selection, metal deficiency responses, biofilm and capsule formation, to the expression of virulence factors. Their research also elucidated the dynamics of these networks and their influence on bacterial population behavior in diverse contexts (e.g., stress, host-pathogen interaction, infection models). Additionally, they identified promising therapeutic targets, explored uncharacterized regions of the S. aureus genome (small RNAs, sORFs, RNA-recognizing proteins, etc.), and, more recently, investigated the impact of epitranscriptomics on S. aureus pathophysiology. Their expertise has fostered numerous collaborations and enhanced international visibility.

The national and international recognition of her work is evident through frequent invitations to international conferences, the organization of international scientific meetings, and several distinctions, including the CNRS Silver Medal (2006) and the Louis Pasteur Medal (2018). Beyond her research activities, she has also played an active role in research evaluation and the coordination of long-term, structuring projects, particularly within the framework of the France Investments for the Future Programs. She also directed the CNRS research unit (UPR9002-ARN) at the IBMC from 2016 to 2023.

The latest winners

Anaïs Astier
July 2026

Anaïs Astier

Centre de Biologie Intégrative (CBI) – Toulouse

Hugo Millat
June 2026

Hugo Millat

IBCP – Lyon

Maximilian Kohl
May 2026

Maximilian Kohl

IBMC (CNRS/Strasbourg University) – Strasbourg

Julius Martinkus
April 2026

Julius Martinkus

LISM (CNRS/Aix-Marseille Université)

Serhii Pankivskyi
March 2026

Serhii Pankivskyi

SABNP laboratory (Université Évry Paris-Saclay)

Safa Boussouar
February 2026

Safa Boussouar

Bioenergetics and Protein Engineering (BIP) laboratory, Marseille

Morgane Roger-Margueritat
January 2026

Morgane Roger-Margueritat

TIMC laboratory, Grenoble

Léa Prochasson and Makram Mghezzi-Habellah
December 2025

Léa Prochasson and Makram Mghezzi-Habellah

Curie Institute and Sorbonne University, Paris

Maëliss Germain
November 2025

Maëliss Germain

Rennes University, BRM Lab. (Bacterial RNAs in Medicine)

Olga Kolosova
October 2025

Olga Kolosova

IGBMC, Strasbourg

Mélisse Hamidi
September 2025

Mélisse Hamidi

Institute of Molecular Microbiology and Structural Biochemistry, Lyon

Zhao Jiangfeng
July and August 2025

Zhao Jiangfeng

EMBL, Grenoble

Robine Maffo Woulefack
June 2025

Robine Maffo Woulefack

Sciences and Technologies Faculty,Vandoeuvre-les-Nancy

Alexia Godet
May 2025

Alexia Godet

Université d’Aarthus, Danemark

Veronica Nuccetteli et Makram Mghezzi
April 2025

Veronica Nuccetteli et Makram Mghezzi

Biology et Cell Modelisation Lab., ENS, Lyon and IBCP, Lyon

Akandé Eyitayo
March 2025

Akandé Eyitayo

IBGC, CNRS, Bordeaux University

Markel Martinez-Carranza
February 2025

Markel Martinez-Carranza

Pasteur Institute, Paris

Nour Ayoub
January 2025

Nour Ayoub

Institut Pasteur Paris, UPCité and INSERM UMRS-1124, Paris

Anaïs Astier

Anaïs Astier

Centre de Biologie Intégrative (CBI) – Toulouse

“Article of the month” award June 2026

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Hugo Millat

Hugo Millat

IBCP – Lyon

“Article of the month” award June 2026

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Maximilian Kohl

Maximilian Kohl

IBMC (CNRS/Strasbourg University) – Strasbourg

“Article of the month” award May 2026

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Julius Martinkus

Julius Martinkus

LISM (CNRS/Aix-Marseille Université)

“Article of the month” award April 2026

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Serhii Pankivskyi

Serhii Pankivskyi

SABNP laboratory (Université Évry Paris-Saclay)

“Article of the month” award March 2026

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Safa Boussouar

Safa Boussouar

Bioenergetics and Protein Engineering (BIP) laboratory, Marseille

“Article of the month” award February 2026

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Morgane Roger-Margueritat

Morgane Roger-Margueritat

TIMC laboratory, Grenoble

“Article of the month” award January 2026

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Léa Prochasson and Makram Mghezzi-Habellah

Léa Prochasson and Makram Mghezzi-Habellah

Curie Institute and Sorbonne University, Paris

“Article of the month”award December 2025

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Maëliss Germain

Maëliss Germain

Rennes University, BRM Lab. (Bacterial RNAs in Medicine)

“Article of the Month” November 2025

 

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Olga Kolosova

Olga Kolosova

IGBMC, Strasbourg

“Article of the Month” award October 2025

 

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Mélisse Hamidi

Mélisse Hamidi

Institute of Molecular Microbiology and Structural Biochemistry, Lyon

“Article of the Month” award September 2025

 

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Zhao Jiangfeng

Zhao Jiangfeng

EMBL, Grenoble

“Article of the Month” award July and August 2025

 

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Robine Maffo Woulefack

Robine Maffo Woulefack

Sciences and Technologies Faculty,Vandoeuvre-les-Nancy

“Article of the Month” award June 2025

 

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Alexia Godet

Alexia Godet

Université d’Aarthus, Danemark

“Article of the month” May 2025

 

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Veronica Nuccetteli et Makram Mghezzi

Veronica Nuccetteli et Makram Mghezzi

Biology et Cell Modelisation Lab., ENS, Lyon and IBCP, Lyon

“Article of the Month” award April 2025

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Akandé Eyitayo

Akandé Eyitayo

IBGC, CNRS, Bordeaux University

“Article of the month” March 2025

 

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Markel Martinez-Carranza

Markel Martinez-Carranza

Pasteur Institute, Paris

“Article of the Month” award February 2025

“Article of the Year” award 2025

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Nour Ayoub

Nour Ayoub

Institut Pasteur Paris, UPCité and INSERM UMRS-1124, Paris

“Article of the Month” award January 2025

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Claire Husser
2026

Claire Husser

CNRS, UPR 9002, Architecture & Reactivity of RNA

Mickaël Guérin
2025

Mickaël Guérin

CNRS, UMR7025, Génie Enzymatique et Cellulaire

Aria Gheeraeart
2024

Aria Gheeraeart

INSERM, Paris

Pauline Herviou
2023

Pauline Herviou

Institut Beatson, Glasgow

Charbel Alfeghali
2022

Charbel Alfeghali

Laboratoire d’Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Nancy

Yoann Santin
2021

Yoann Santin

Institut de Duve, Bruxelles

Florent Waltz
2020

Florent Waltz

Université de Strasbourg

Juliette Fédry
2019

Juliette Fédry

Institut Pasteur, Paris

Clément Charenton
2018

Clément Charenton

École Polytechnique, Palaiseau

Thomas Eychenne
2017

Thomas Eychenne

CEA, Saclay

Claire Husser

Claire Husser

CNRS, UPR 9002, Architecture & Reactivity of RNA

Dina Surdin award 2026

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Mickaël Guérin

Mickaël Guérin

CNRS, UMR7025, Génie Enzymatique et Cellulaire

Dina Surdin award winner 2025

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Aria Gheeraeart

Aria Gheeraeart

INSERM, Paris

Dina Surdin award 2024

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Pauline Herviou

Pauline Herviou

Institut Beatson, Glasgow

Dina Surdin award 2023

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Charbel Alfeghali

Charbel Alfeghali

Laboratoire d’Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Nancy

Dina Surdin award 2022

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Yoann Santin

Yoann Santin

Institut de Duve, Bruxelles

Dina Surdin award 2021

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Florent Waltz

Florent Waltz

Université de Strasbourg

Dina Surdin award 2020

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Juliette Fédry

Juliette Fédry

Institut Pasteur, Paris

Dina Surdin award 2019

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Clément Charenton

Clément Charenton

École Polytechnique, Palaiseau

Dina Surdin award 2018

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Thomas Eychenne

Thomas Eychenne

CEA, Saclay

Dina Surdin award 2017

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Apply for the Dina Surdin Award

Applications must be submitted in March. The exact deadline is announced each year by email.

Documents to be submitted:
Downloadable application guidelines document below, a copy of the thesis manuscript.

Download the application guidelines
Pascale Romby
2025

Pascale Romby

CNRS, UPR 9002, ARN “RNA Architecture and Reactivity”, IBMC, Strasbourg

Pascale Lesage
2024

Pascale Lesage

CNRS et équipe de Biologie de l’instabilité des génomes, Paris

Carine Tisné
2023

Carine Tisné

IBPC, Paris

Pascale Romby

Pascale Romby

CNRS, UPR 9002, ARN “RNA Architecture and Reactivity”, IBMC, Strasbourg

Marianne Grunberg-Manago award 2025

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Pascale Lesage

Pascale Lesage

CNRS et équipe de Biologie de l’instabilité des génomes, Paris

Marianne Grunberg-Manago award 2024

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Carine Tisné

Carine Tisné

IBPC, Paris

Marianne Grunberg-Manago award 2023

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Apply for the Marianne Grunberg-Manago Award

Applications must be submitted by email to martin.picard@ibpc.fr. The exact deadline will be announced annually via email.

Required Documents:
Updated CV, including a summary of the candidate’s work and publications, formatted according to the downloadable guide below.

Any application received after the specified deadline will not be considered.

Download the application guidelines
Etienne BLANC
2026

Etienne BLANC

Institute for Research in Health, Environment and Work – INSERM UMRS 1035 – Rennes

Laure-Emmanuelle Zaragosi
2025

Laure-Emmanuelle Zaragosi

Inserm, IPMC, Sophia-Antipolis

Maxime Wery
2024

Maxime Wery

Institut Curie, Paris

Tamara Basta-Le-Berre
2023

Tamara Basta-Le-Berre

CNRS, UMR9198, Institut de Biologie Intégrative de la Cellule (I2BC), Gif-sur-Yvette

Ludovic Pelosi
2022

Ludovic Pelosi

Laboratoire UGA (Groupe Quinones Respiratoires), Grenoble

Cyril Bourgeois
2021

Cyril Bourgeois

ENS, Lyon

Célia Plisson-Chastang
2020

Célia Plisson-Chastang

CNRS, UMR 5099, Toulouse

Odil Porrua
2019

Odil Porrua

CNRS, UMR7592 (Institut Jacques Monod), Paris

Hervé Seitz
2018

Hervé Seitz

CNRS, UMR 9002 (Institut de génétique humaine), Montpellier

Michaël Ryckelynck
2017

Michaël Ryckelynck

Biologie Digitale de l’ARN, UPR 9002, Architecture et réactivité de l’ARN, IBMC, Strasbourg.

Martin PICARD
2016

Martin PICARD

CNRS UMR 7099, Laboratoire de Biologie Physico-chimique des protéines membranaires, IBPC

Etienne BLANC

Etienne BLANC

Institute for Research in Health, Environment and Work – INSERM UMRS 1035 – Rennes

Maurice Nicloux Award 2026

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Laure-Emmanuelle Zaragosi

Laure-Emmanuelle Zaragosi

Inserm, IPMC, Sophia-Antipolis

Maurice Nicloux Award 2025

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Maxime Wery

Maxime Wery

Institut Curie, Paris

Maurice Nicloux award 2024

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Tamara Basta-Le-Berre

Tamara Basta-Le-Berre

CNRS, UMR9198, Institut de Biologie Intégrative de la Cellule (I2BC), Gif-sur-Yvette

Maurice Nicloux award 2023

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Ludovic Pelosi

Ludovic Pelosi

Laboratoire UGA (Groupe Quinones Respiratoires), Grenoble

Maurice Nicloux award 2022

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Cyril Bourgeois

Cyril Bourgeois

ENS, Lyon

Maurice Nicloux award 2021

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Célia Plisson-Chastang

Célia Plisson-Chastang

CNRS, UMR 5099, Toulouse

Maurice Nicloux award 2020

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Odil Porrua

Odil Porrua

CNRS, UMR7592 (Institut Jacques Monod), Paris

Maurice Nicloux award 2019

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Hervé Seitz

Hervé Seitz

CNRS, UMR 9002 (Institut de génétique humaine), Montpellier

Maurice Nicloux award 2018

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Michaël Ryckelynck

Michaël Ryckelynck

Biologie Digitale de l’ARN, UPR 9002, Architecture et réactivité de l’ARN, IBMC, Strasbourg.

Maurice Nicloux award 2017

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Martin PICARD

Martin PICARD

CNRS UMR 7099, Laboratoire de Biologie Physico-chimique des protéines membranaires, IBPC

Maurice Nicloux award 2016

Discover the laureate

Apply for the Maurice Nicloux Award

Applications must be submitted by March of each year. The exact deadline will be announced annually via email.

Required Documents:
Updated CV, including a summary of the candidate’s work and publications, formatted according to the downloadable guide below.

Any application received after the specified deadline will not be considered.

Download the application guidelines

Our scientific awards

“Article of the Month” award

Honors a young researcher for a paper published in a peer-reviewed journal.

Dina Surdin award

Rewards a young researcher for an outstanding PhD thesis in biochemistry or molecular biology.

Marianne Grunberg-Manago Award

Honors a woman who has made an outstanding contribution to public research, recognized for the significance of her work and her impact in her scientific field.

Maurice Nicloux award

Honors an established researcher for their overall contribution to the scientific community and to research in biochemistry or molecular biology.