Cyril Bourgeois
Maurice Nicloux award winner 2021
Profile
Cyril Bourgeois has dedicated his entire career to studying the molecular mechanisms of gene expression in higher eukaryotes, with a particular focus on the regulation of alternative splicing. He has approached this topic through both purely biochemical methods and large-scale approaches. During his PhD, defended in 1999 in James Stévenin’s team at the IGBMC (Illkirch/Strasbourg), he explored the interactions between certain splicing factors and their target RNA sequences, as well as the impact of these interactions on the control of alternative splicing. He then completed a postdoctoral fellowship in Jonathan Karn’s team (first at the LMB in Cambridge, UK, and later at Case Western Reserve University in Cleveland, USA), where he studied the mechanisms regulating transcriptional elongation, using the HIV-1 virus and its Tat protein as a model.
After returning to the IGBMC in 2003 following his recruitment at INSERM, Cyril resumed his research on splicing factors, incorporating a more applied dimension by studying various pathological conditions (genetic diseases and cancer). His work contributed to the development of diagnostic approaches to predict protein binding to a given RNA motif, whether mutated or not, as well as therapeutic strategies to correct or alter the splicing of specific transcripts.
In 2011, he joined Didier Auboeuf’s team at the Cancer Research Center of Lyon and, since 2015, at the ENS de Lyon. There, he developed new expertise in transcriptome analysis and contributed to the development of bioinformatics tools aimed at identifying global splicing variations and predicting their functional consequences. He leads a research group focused on the diverse functions of two RNA helicases (DDX5 and DDX17) in gene expression. The study of these factors has led him to consider gene expression from a more integrated perspective, within a chromatin context that links RNA maturation to the control of transcriptional dynamics and the spatial folding of genes.
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Aria Gheeraeart
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Pauline Herviou
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Charbel Alfeghali
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Yoann Santin
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Florent Waltz
Université de Strasbourg
Juliette Fédry
Institut Pasteur, Paris
Clément Charenton
École Polytechnique, Palaiseau
Thomas Eychenne
CEA, Saclay
Apply for the Dina Surdin Award
Applications must be submitted in March. The exact deadline is announced each year by email.
Documents to be submitted:
Downloadable application guidelines document below, a copy of the thesis manuscript.
Pascale Romby
CNRS, UPR 9002, ARN “RNA Architecture and Reactivity”, IBMC, Strasbourg
Pascale Lesage
CNRS et équipe de Biologie de l’instabilité des génomes, Paris
Carine Tisné
IBPC, Paris
Apply for the Marianne Grunberg-Manago Award
Applications must be submitted by email to martin.picard@ibpc.fr. The exact deadline will be announced annually via email.
Required Documents:
Updated CV, including a summary of the candidate’s work and publications, formatted according to the downloadable guide below.
Any application received after the specified deadline will not be considered.
Laure-Emmanuelle Zaragosi
Inserm, IPMC, Sophia-Antipolis
Maxime Wery
Institut Curie, Paris
Tamara Basta-Le-Berre
CNRS, UMR9198, Institut de Biologie Intégrative de la Cellule (I2BC), Gif-sur-Yvette
Ludovic Pelosi
Laboratoire UGA (Groupe Quinones Respiratoires), Grenoble
Cyril Bourgeois
ENS, Lyon
Célia Plisson-Chastang
CNRS, UMR 5099, Toulouse
Odil Porrua
CNRS, UMR7592 (Institut Jacques Monod), Paris
Hervé Seitz
CNRS, UMR 9002 (Institut de génétique humaine), Montpellier
Michaël Ryckelynck
Biologie Digitale de l’ARN, UPR 9002, Architecture et réactivité de l’ARN, IBMC, Strasbourg.
Martin PICARD
CNRS UMR 7099, Laboratoire de Biologie Physico-chimique des protéines membranaires, IBPC
Apply for the Maurice Nicloux Award
Applications must be submitted by March of each year. The exact deadline will be announced annually via email.
Required Documents:
Updated CV, including a summary of the candidate’s work and publications, formatted according to the downloadable guide below.
Any application received after the specified deadline will not be considered.
Our scientific awards
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Honors a young researcher for a paper published in a peer-reviewed journal.
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Rewards a young researcher for an outstanding PhD thesis in biochemistry or molecular biology.
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Honors a woman who has made an outstanding contribution to public research, recognized for the significance of her work and her impact in her scientific field.
Maurice Nicloux award
Honors an established researcher for their overall contribution to the scientific community and to research in biochemistry or molecular biology.