Pauline Herviou
Dina Surdin award winner 2023
Profile
Pauline Herviou, earned her engineering degree (specializing in biotechnologies) in 2018 from AgroParisTech (Paris Institute of Life Sciences, Food and Environmental Technology). She then completed her PhD under the supervision of Dr Anne Cammas and Dr Stefania Millevoi at the Cancer Research Center of Toulouse (CRCT).
Her PhD project focused on the function of RNA G-quadruplexes (RG4) in mRNA translation and the consequences of these regulations on tumor progression and resistance to anti-cancer therapies. Her work first identified the RNA-binding proteins (RBPs) hnRNP H/F as key components of the machinery regulating RG4 structuring. She then demonstrated that these factors collaborate with the RNA helicase DHX36 to control the translation of mRNAs containing RG4s, which encode proteins involved in the cellular response to genotoxic stress. This study not only established a link between RG4-dependent translation and genetic instability but also associated this link with a role in resistance to genotoxic treatments in glioblastomas, a type of brain tumor with a very poor prognosis. Her work also identified RG4s as regulators of autophagy, a crucial mechanism for maintaining cellular homeostasis under stress and linked to tumor development and resistance to anti-cancer therapies. Overall, the results of her thesis demonstrate that RG4-RBP interactions play a central role in translational control associated with the stress response, thereby contributing to tumor development and treatment resistance.
After her PhD, she joined Prof. Martin Bushell’s laboratory at the Cancer Research UK Beatson Institute in Glasgow (UK) as a post-doctoral researcher. She is currently studying the role of eIF4A2 in controlling the localization and translation of mRNAs translated at the endoplasmic reticulum.
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Charbel Alfeghali
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Apply for the Dina Surdin Award
Applications must be submitted in March. The exact deadline is announced each year by email.
Documents to be submitted:
Downloadable application guidelines document below, a copy of the thesis manuscript.
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Apply for the Marianne Grunberg-Manago Award
Applications must be submitted by email to martin.picard@ibpc.fr. The exact deadline will be announced annually via email.
Required Documents:
Updated CV, including a summary of the candidate’s work and publications, formatted according to the downloadable guide below.
Any application received after the specified deadline will not be considered.
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Maurice Nicloux award 2024
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Maurice Nicloux award 2023
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Maurice Nicloux award 2022
Cyril Bourgeois
ENS, Lyon
Maurice Nicloux award 2021
Célia Plisson-Chastang
CNRS, UMR 5099, Toulouse
Maurice Nicloux award 2020
Odil Porrua
CNRS, UMR7592 (Institut Jacques Monod), Paris
Maurice Nicloux award 2019
Hervé Seitz
CNRS, UMR 9002 (Institut de génétique humaine), Montpellier
Maurice Nicloux award 2018
Michaël Ryckelynck
Biologie Digitale de l’ARN, UPR 9002, Architecture et réactivité de l’ARN, IBMC, Strasbourg.
Maurice Nicloux award 2017
Martin PICARD
CNRS UMR 7099, Laboratoire de Biologie Physico-chimique des protéines membranaires, IBPC
Maurice Nicloux award 2016
Apply for the Maurice Nicloux Award
Applications must be submitted by March of each year. The exact deadline will be announced annually via email.
Required Documents:
Updated CV, including a summary of the candidate’s work and publications, formatted according to the downloadable guide below.
Any application received after the specified deadline will not be considered.
Our scientific awards
“Article of the Month” award
Honors a young researcher for a paper published in a peer-reviewed journal.
Dina Surdin award
Rewards a young researcher for an outstanding PhD thesis in biochemistry or molecular biology.
Marianne Grunberg-Manago Award
Honors a woman who has made an outstanding contribution to public research, recognized for the significance of her work and her impact in her scientific field.
Maurice Nicloux award
Honors an established researcher for their overall contribution to the scientific community and to research in biochemistry or molecular biology.
