Preclinical mouse models are widely used for studying mechanisms of disease and responses to therapeutics, however there is concern about the lack of experimental reproducibility and failure to predict translational success. The gut microbiome has emerged as a regulator of metabolism and immunological processes in health and disease.
Bari's University, Italie « Inhibition of LPAR6 overcomes sorafenib resistance by switching glycolysis into oxidative phosphorylation in hepatocellular carcinoma »
https://doi.org/10.1016/j.biochi.2022.07.016
Davide Gnocchi, Agata Kurzyk, Antonella Mintrone, Giovanni Lentini, Carlo Sabba and Antonio Mazzocca.
College of Korea Medicine, Kyung Here University, #47, Kyungheedae-gil
"Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway. "
(2020) BIOCHIMIE 175, 58-68. DOI: 1016/j.biochi.2020.05.006
Dr Jong Hyun Lee
Calvin University, Department of Chemistry & Biochemistry, Grand Rapids, MI, USA
"Cellular binding and uptake of fluorescent glucose analogs 2-NBDG and 6-NBDG occurs independent of membrane glucose transporters."
(2021) BIOCHIMIE 190, 1-11. DOI: 10.1016/j.biochi.2021.06.017