Cv

Assia Mouhand, 27 years old, obtained a bachelor’s degree in chemistry / biochemistry , a Master’s degree "Structural and Functional Engineering of Biomolecules". She recently completed her thesis in the laboratory of Biological Cristallography and NMR (Univertsity of Paris Decartes) and the Laboratory of Microbial Genetic Expression (Institute of Physico-Chemical Biology – Paris) under the supervision of Dr. Carine Tisné. Her work published in Nucleic Acid Research focused on the NMR study of HIV-1 nucleocapsid protein, alone and interacting with its different partners during the viral cycle, in order to understand its role in the HIV assembly and budding. Her work highlights the roles of intrinsically disordered proteins (IDPs) in many biological processes. In this context, her publication presents a cooperation of intrinsically disordered domains and structured domains, constituting the nucleocapsid protein, for the recruitment of their respective partners and the function of these unstructured domains during assembly and budding of virions. She gets recently a post-doctoral position in Dr. Pau Bernado’s team, at the Center of Structural Biochemistry in Montpellier to study with Dr. Nathalie Sibille, function of C-terminal domain (which is intrinsically disordered) of G-protein coupled receptors in cell signal induction.