Job opening for postdoctoral researcher to join the “mRNA processing” team at IGBMC, Strasbourg.

The newly created “mRNA maturation” team at IGBMC (Strasbourg, France) is looking for a postdoc to join the SPLIFEM project funded by an ERC Starting Grant.

This position would be ideal for a biochemist and/or structural biologist (cryo-EM/crystallography) interested in the structure and function of large protein/RNA assemblies.

The selected candidate will carry out a mechanistic study of the human spliceosome aimed at unravelling how it ensures the fidelity of pre-mRNA splicing. For this, the researcher will use a combination of biochemical and structural biology methods: ribonucleoprotein complexes reconstitution from cell extracts and/or recombinant sources, cryo-EM, X-ray crystallography, mass spectrometry… The IGBMC has an exceptional scientific environment particularly well suited for this ambitious project. In particular, the institute hosts several cutting-edge technological platforms (electron microscopy equipped with two Titan Krios and a Glacios; cell culture; protein production; molecular biology; mass spectrometry, etc.)

Candidates with relevant background (biochemistry and/or structural biology) and motivated by such a project are encouraged to apply by sending a CV and a cover letter to the team leader, Clément Charenton.

Ideally, this position is to be filled from the summer of 2023 and for a period of two years. Salary will depend on applicant's experience.

Contact: charentc@igbmc.fr