Société Française de Biochimie et Biologie Moléculaire

Genetic code: Mechanisms, Evolution and Engineering

Genetic code: Mechanisms, Evolution and Engineering

The genetic code was unraveled some 55 years ago, in a short period of time, but through arduous and insightful chemical and biochemical experimental designs. Formally, the genetic code is a cypher, a frozen table of correlations between two sets of letters with few variations. Viewed at the molecular level, however, the code as we know it now appeared in stages, resulting from the complex molecular recognition and selection processes full of contingencies at the core of the transition from chemistry to biology in biological evolution. In the last twenty years, a wealth of structures of active ribosomes and components of the translation apparatus has appeared. We now have a rich diversity of structures at sufficient resolution to integrate biochemical and biological observations in congruence with molecular data.

In this meeting, these structural constraints will be described with their functional and organizational impacts on the cellular integration and homeostasis analyzed from various angles. Fifteen internationally renowned speakers, from four different European countries, have already accepted to present their last results. They will speak on four broad themes: ribosome structures and decoding, translational variations and miscoding, evolution and code optimization, ribosome engineering and code expansion. Topics will cover structures and kinetics of translation, neuronal translation, the interplay between translation and metabolism, the origins of the code and metabolism, and engineering of the code. Most importantly, twenty slots are kept for talks chosen from the received abstracts. This process will give the opportunity to speak to young scientists and allow for unexpected or recent new results to be presented and discussed. Two poster sessions are also planned to encourage exchange and discussions.

We are looking forward to meeting you next year in Strasbourg.

                        Eric Westhof,

                        Chair of the Scientific Commmittee

                        Professor emeritus - University of Strasbourg

                        Member of the French Academy of Sciences

Informations complémentaires



Le congrès « Genetic Code : Mechanisms, Evolution and Engineering» est organisé par deux sociétés scientifiques françaises renommées : La Société Française de Génétique et la Société Française de Biochimie et Biologie Moléculaire.

Il rassemblera principalement les chercheurs européens travaillant dans ce domaine.

Cette thématique liée à la question fondamentale de l’origine de la vie, en permettant la confrontation des hypothèses, conduira à de nouvelles synthèses génératrices d’avancées des connaissances scientifiques.

Le site et les participants

Seront présents 150 participants, avec des conférenciers invités de renommée mondiale.

Le congrès aura lieu au Centre Culturel Saint-Thomas, proche des Institutions Européennes. Ce site a été choisi car il maximalise les possibilités de rencontres entre conférenciers renommés et les jeunes poussent (Doctorants et post-Doctorants) en proposant sur place, pauses, déjeuners et dîners.